A Novel Species-selective Rodenticide: a Humane, Environmentally Safe Solution to Protect Biodiversity and Agriculture

Field

A Novel Species-selective Rodenticide: a Humane, Environmentally Safe Solution to Protect Biodiversity and Agriculture

2025 YPS Grant Project

Traditional rodenticides have caused raptor decline and endangered species loss leading to proposed legislation banning their use. These poisons act slowly, causing prolonged suffering and resistance buildup, while contaminating ecosystems and harming natural predators. This project team is developing a humane and environmentally responsible rodenticide that is mouse-specific. Unlike conventional rodenticides, it is non-toxic and non-accumulative in other species. This solution aims to mitigate environmental harm and biodiversity loss to meet the demands of increasing regulatory restrictions. In vivo proof-of-concept studies will lay the groundwork for commercialization and stakeholder engagement.

Participants

  • Craig M Crews

    John C. Malone Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry, of Pharmacology, and of Management

  • Jonathan Birabaharan

    Blavatnik Fellow